Russian researchers from IPMS RAS, NUST MISIS, N.N. Blokhin National Medical Research Center of Oncology, LPI RAS, IOG RAS, Belgorod State University, and the Liaoning Academy of Materials have presented an improved biodegradable alloy based on iron and manganese, which dissolves in the body twice as fast compared to analogues. A key factor in the accelerated degradation was the addition of silicon and the use of high pressure during material processing – up to 60 thousand atmospheres.
Experiments have shown that silicon promotes martensitic transformation – a rearrangement of the crystal lattice, in which atoms are displaced by distances smaller than interatomic distances. This accelerates the corrosion of the alloy in a biological environment, reducing its dissolution time to 1–2 years.
The authors of the study plan to scale up the development to obtain prototypes of products and conduct clinical trials on animals and humans. Such material is especially in demand in orthopedics, oncology, and veterinary medicine, where temporary implants should support tissues only during the recovery phase. Details of the study are published in the journal Crystals.
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