Изобретённые в Сеченовском университете сетчатые импланты снижают риски осложнений после гинекологических операций

Sechenov University has developed an innovative approach to treating pelvic organ prolapse, a common gynecological problem affecting up to 30% of women. Traditional surgical correction methods do not always provide long-term results: recurrences occur in 30% of cases, and the use of synthetic materials sometimes leads to complications.

Image source Press service of Sechenov University

The new technique is based on cell-engineered constructs – mesh implants seeded with autologous fibroblasts (connective tissue cells from the patient herself). This reduces the risk of rejection, as the body perceives the implant as "its own." The technology has been successfully tested in animal experiments and then applied in clinical practice.

The result is a material that is practically "native" to the woman. In this way, we can outsmart the body by passing off the mesh as its own tissue.

Anatoly Ishchenko, Director of the Clinic of Obstetrics and Gynecology at Sechenov University

During the pilot operations, titanium meshes seeded with fibroblasts taken from the patients' skin were used. After three months of observation, no complications were detected, and organ function was fully restored. In the future, the method is planned to be used for other pathologies, including Asherman's syndrome and congenital vaginal anomalies.

The study showed that the constructs are suitable for implantation, do not cause rejection, and form more mature connective tissue. It is assumed that in the future, the method will minimize the likelihood of complications.

Anatoly Ishchenko, Director of the Clinic of Obstetrics and Gynecology at Sechenov University

Classic propylene implants, despite their widespread use, can cause chronic inflammation and tissue deformation. Titanium silk, previously patented at Sechenov University, has already shown better biocompatibility. The new method with autologous cells may be the next step in reducing postoperative risks.

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