Scientists at the Russian Technological University (RTU MIREA) have developed a new combined drug against cancer that combines two methods of воздействие on the tumor — chemotherapy and photodynamic therapy. The drug is based on platinum compounds and natural chlorins. This combination can significantly increase the effectiveness of cancer treatment and reduce toxicity compared to traditional approaches.
Platinum drugs, such as cisplatin and carboplatin, have long been used in oncology, but are accompanied by serious side effects and are often ineffective against resistant tumors. Chlorins, in turn, are able to accumulate directly in cancer cells and, when activated by light, generate reactive oxygen species that destroy tumor tissue. Combining these mechanisms in one compound allows воздействие on the tumor systemically and locally simultaneously.
The authors of the project found a way to incorporate platinum complexes into the structure of chlorins, obtaining chemically stable hybrid compounds. The new approach helps to overcome both the toxicity of platinum drugs and the limitations of photodynamic therapy, which previously could only be used for superficial tumors.
The development, according to researchers, opens the way to new types of therapy for aggressive and treatment-resistant forms of cancer and may become the basis for creating more effective and safe cancer drugs.
Read materials on the topic:
Fighting cancer: a biocomposite created in Russia to fight melanoma
A facility for treating the most complex types of cancer has been created in Novosibirsk
Rosatom has developed a new technology for producing a drug for cancer treatment
Now on home
Герой России Гарнаев: никто из профессионалов о возобновлении производства на КАЗ всерьёз не говорит
Система отслеживает спутники на высотах до 50 000 км и ведёт за ними наблюдение
The armored vehicle is equipped with a KamAZ-740.35-400 diesel engine with a power of 400 hp.
Constant improvements in avionics, weapons and tactical capabilities will make the aircraft a flexible response to future challenges
The exterior of the KamAZ-54901 features fairings on the cab and chassis for fuel economy
Fighters are in demand both domestically and abroad
Tyazhpromexport and Venezuela Agree on Plant Revival
The company not only completed the state order, but also quickly mastered the production of AK-12K for special forces
Experts have developed a photogrammetric complex with a resolution of less than 1 cm
