Scientists from Skoltech have developed an algorithm based on generative artificial intelligence that can restore missing data on the location of genes in DNA. This method allows for highly accurate determination of distances between genes even with incomplete initial data, which can significantly accelerate research in the field of genetics and medicine.
As explained by Kirill Polovnikov, Senior Lecturer at Skoltech, the task of determining the distances between genes based on a limited set of data comes down to a mathematical problem that can now be solved using generative models.
If we know the distances between a sufficient number of gene pairs, the search for distances between the remaining pairs, for which there is no experimental data, takes the form of a mathematical problem with a specific solution. We have shown for the first time that such problems can be solved by generative models, which is an atypical area for their application.
The human genome consists of long strands of DNA packed into chromosomes. Understanding their three-dimensional structure is important for studying the functioning of genes and their influence on the development of diseases. Traditional methods, such as fluorescence microscopy (FISH), do not always allow obtaining complete data due to technical limitations. Russian scientists have proposed using generative AI to fill these gaps, similar to how neural networks complete images.
During the experiment, the DDRM algorithm successfully restored the missing data on a section of human chromosome 21, surpassing classical methods. This opens up prospects for faster and more accurate genome analysis, which is critical for the development of new drugs and methods for diagnosing hereditary diseases.
Read more on the topic:
Now on home
Start of deliveries scheduled for 2027
Over 51,000 new motorcycles were sold in Russia in 2025
The car will take at least a year to assemble
The application's audience has reached 20 million users
The model will be included in the list of cars for taxis, price - from 2.25 million rubles
All parking lots of the "Administrator of the Moscow Parking Space" are connected to the service
The cars will be supplied to the Moscow Transport Service Directorate
Deliveries to India may begin in 2028
The technology provides automated search for all types of defects in power units
The plane flew 500 km, accelerating to 425 km/h
The plant stated that the information about the termination of purchases for models 6 and 8 is not true
Scientists are using the "Ekran-M" installation