Российские исследователи представили инновационный костный цемент

Bone cement created, clearly visible on tomographic images

Russian researchers have developed a new bone cement that serves as a replacement for existing polymethylmethacrylate (PMMA)-based materials for bone tissue replacement. This innovative material is based on calcium and magnesium phosphates and contains gadolinium ions, allowing it to be visualized on images obtained using computed tomography and magnetic resonance imaging. The press service of the Russian Science Foundation (RSF) noted that the new cement has significant advantages, including strength, antimicrobial effect, and biocompatibility.

The development aims to improve existing solutions, which often have drawbacks such as low biocompatibility and high setting temperature, which can damage surrounding tissues. The new bone cement, created on the basis of calcium and magnesium phosphates, demonstrates high mechanical properties and promotes the growth of natural bone tissue. In addition, it turns into brushite and newberyite minerals even at room temperature, which makes its application process safer.

Thanks to the addition of gadolinium ions, the new cement becomes easily distinguishable on tomographic images. These ions change the interaction between hydrogen atoms and tomograph radiation, increasing image contrast. This property will allow doctors to see more accurately where the cement has been placed in the patient's body.

Also, studies have shown that the new bone cement has antibacterial properties, which reduces the risk of infections after surgical interventions. Preclinical trials have demonstrated high compatibility of the material with human cells, paving the way for clinical trials, which scientists intend to begin in the near future.

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