St. Petersburg State Electrotechnical University (LETI) has presented the innovative ReGenesis Box system. The development will increase the storage time of donor lungs by 4–12 times compared to existing counterparts, according to the university's press service.
One of the main problems in organ transplantation remains the shortage of donor material. To solve this problem, effective means for perfusion are needed. They ensure the long-term preservation of organ viability until transplantation.
The ReGenesis Box system uses a special plasma-substituting solution to saturate donor lungs with oxygen and nutrients. The system's software controls the sensors. They monitor the parameters of the internal environment, the operation of the pump, and the temperature regime.
Unlike traditional cold preservation, it allows increasing the viability of organs from 4–6 hours to 24 hours or more, potentially reaching 72 hours. This approach to preserving donor organs reduces the risk of ischemic damage and increases the percentage of successful transplants from 70% to 90%.
So far, scientists have developed a digital twin of the ReGenesis Box system. It allows visually demonstrating the perfusion process with high accuracy.
Next year, it is planned to start designing the device, and then specialists will conduct preclinical trials.
Earlier, www1.ru reported that Russian scientists invented how to preserve artificial organs without losing their properties.
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