Specialists from Sechenov University have developed a unique aortic valve from donor pericardium (pericardial sac). This is the world's first biological valve based on homologous pericardium, the university said.
Cardiac surgeons have come up with a special method for processing biological material and a storage solution. With its help, the valve elements do not calcify - and this is one of the problems with organ implantation.
The press service of Sechenov University clarified that such an aortic valve will last 40% longer than its analogues. Consequently, the period for installing a biological prosthesis will approach a lifetime.
Valve implantation is indicated for patients with cardiovascular diseases, including congenital heart defects, heart failure, and stenosis
Now, cardiac surgeons are conducting studies of experimental valve samples on a pulse duplicator. Then they plan to implant them into laboratory animals. After positive results of preclinical studies, clinical testing will begin. It is expected that the aortic prosthesis will be implanted in middle-aged patients.
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