As part of the 75th mission to the ISS, specialists are beginning the second stage of research into bone loss in microgravity conditions, TASS reported from the Institute of Biomedical Problems (IMBP) of the Russian Academy of Sciences. The "Correction" experiment aims to answer how exactly weightlessness destroys the bone structure and whether this process can be reversed after returning to Earth.
Scientists will evaluate the effectiveness of pharmacological correction of mineral metabolism during a long flight. The program includes biomaterial sampling for biochemical marker analysis, measurement of bone mass, geometry, and structure before and after the flight, as well as monitoring of crew nutrition to assess bone tissue metabolism. The minimum task is to describe the dynamics of loss and recovery; the maximum task is to learn how to predict the reversibility of changes.
In addition, IMBP RAS will conduct two more experiments. "Forced Exhalation" will test how the lungs work in zero gravity – for this, cosmonauts' tracheal sounds will be recorded. "Virtual" will assess the spatial orientation and sensory adaptation of the crew.
Such a triple measurement – bone, respiration, vestibular apparatus – gives doctors a holistic picture of how the body adapts outside of gravity and brings them closer to creating protection protocols for future long-duration missions.
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