Russian scientists have tested a portable bioprinter that can accelerate skin regeneration after severe damage. The device applies a special gel with cellular structures to the wound, gradually forming new tissue. The technology was developed by specialists from Sechenov University.
The material's base was a hydrogel made of fibrin and gelatin. Spheroids formed from mesenchymal stromal cells of adipose tissue were added to it.
The system was tested in a preclinical experiment on mini-pigs with ischemic skin lesions. Such wounds have poorer blood supply and heal significantly slower than usual.
By day 18, the area of wounds treated with the composition containing cellular spheroids decreased by approximately 90%. In the control groups, the reduction ranged from 30 to 40%. The damaged area decreased to 1.3 square centimeters compared to 10–11 square centimeters in other groups.
By day 36, researchers recorded the restoration of all skin layers. In the control groups, healing had not yet completed by this time.
The development has so far passed the preclinical stage. The technology has not yet become a ready-made treatment method for humans. It will undergo further safety and efficacy tests.



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