Four New Technetium Compounds for Medicine Synthesized by IPCE RAS and MSU

Nitrogen bridge and different oxidation states will expand the possibilities of radiodiagnostics

Chemists from IPCE RAS, in collaboration with MSU, have synthesized four new nitride complexes of technetium — a metal whose isotopes are key for radiodiagnostics. According to the Ministry of Education and Science of the Russian Federation, the structures of the compounds vary greatly: products with oxidation states of +5 and +6 were obtained.

The complex with benzothiazole became unique: two technetium atoms are connected by a nitrogen bridge (one nitrogen connects to both metals). Previously, such compounds did not exist. It was not possible to obtain a crystalline product with pyrimidine.

Technetium is "packaged" in a carrier molecule for delivery to the heart or brain. New data on the stability and formation conditions of complexes will allow for more accurate creation of radiopharmaceuticals and safer processing of nuclear materials.

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Sources:
Tass Agency

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