Scientists from Perm State Medical University (PSMU) and Perm National Research Polytechnic University (PNRPU) have made a significant step in the field of medicine. Researchers have patented an innovative technology that allows predicting the development of tumors in the frontal lobe of the brain even before the first symptoms appear. The method is based on a comprehensive approach that includes the analysis of various parameters associated with the risk of developing neoplasms.
Detecting tumors in the frontal lobe of the brain is a complex task, as their detection requires high-tech methods at early, often asymptomatic stages. Scientists from PSMU and PNRPU have developed a unique approach that allows predicting the development of the disease before clinical signs appear.
Difficulties of diagnosis and unique approach
Frontal lobe of the brain: the largest part of the brain. It is responsible for many important functions, including planning, decision-making, motor skills, memory, and social behavior. Tumors in this area can develop for a long time without obvious symptoms, and their signs become noticeable only when the tumor has significantly increased, causing increased intracranial pressure or disrupting the functioning of neurons.
The developed method for predicting tumors is based on collecting the patient's medical history and conducting magnetic resonance imaging (MRI) to measure parameters in the precentral gyrus of the brain. This area plays a critical role in controlling voluntary movements and is very sensitive to pathological changes. Scientists propose to monitor changes in the width of the gyrus and the thickness of the cerebral cortex, which may signal possible problems associated with oncological diseases.
Diagnostic process and its effectiveness
As part of the new technology, the doctor must identify five risk factors that the patient faces in their life. These include: increased intracranial pressure, prolonged neurological symptoms (such as headaches and cognitive impairments), the presence of genetically determined diseases in relatives, exposure to radioactive radiation, and work in hazardous industries.
After that, with the help of MRI, accurate measurements are taken in the precentral gyrus, including the width and thickness of the cerebral cortex at three strictly defined points. As a result, the doctor receives 12 parameters, which are compared with the normative values corresponding to the patient's gender and age. If at least one risk factor is confirmed and two or more parameters are outside the normal range, this may indicate the likelihood of developing a tumor.
The method also allows determining the possible location of the neoplasm. Studies conducted on 445 patients have confirmed the high prognostic value of the combination of anamnestic data and changes in the structure of the brain.
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