Specialists from the Ogarev Mordovia State University have developed the world's first biocompatible tubular structures for the regeneration of damaged somatic nerves. The material, based on bacterial cellulose and polyvinyl alcohol, is twice as strong as analogues and contains components that stimulate the growth of nerve cells.
The new conduits (artificial nerve guides) were created by culturing bacterial cellulose on a molasses medium and then modifying it with polyvinyl alcohol. This increased the tensile strength of the material by two times compared to ordinary cellulose. Physiologically active compounds are also integrated into the structures, which activate signaling pathways responsible for the survival and recovery of neurons.
Modern methods do not provide long-term support for nerve regeneration. Our material solves this problem by creating an optimal environment for neurite growth
Peripheral nerve damage is one of the main causes of disability. Existing implants are not able to support recovery processes for long. The development of Mordovian scientists allows accelerating regeneration, reducing the rehabilitation time of patients after injuries or operations. The bacterial cellulose used in the conduits is biologically inert and does not cause rejection.
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