Researchers from Sechenov University were able to 3D-print a tympanic membrane from living cells and collagen.
To restore tympanic membrane perforation, we decided to create new and more complex tissue-engineered constructs for us. We took previously developed bio-inks containing biocompatible hydrogel and cell spheroids as a basis. Then, using a 3D bioprinter on bio-paper, which was collagen matrices, we printed constructs.
Millions of people around the world suffer from tympanic membrane perforation, which leads to deafness or hearing loss. The new technology will allow people to restore hearing within a month. In addition, the operation with it will be many times faster than usual - about 40 minutes.
Researchers have already conducted experiments on chinchillas (their membrane is very similar to the human one), and plan to conduct clinical trials.